The journal CardioRenal Medicine explores the mechanisms by which obesity and other metabolic abnormalities promote the pathogenesis and progression of heart and kidney disease (cardiorenal metabolic syndrome). It provides an interdisciplinary platform for the advancement of research and clinical practice, focussing on translational issues.Attention is paid to the fact that some metabolic abnormalities cluster with heart and chronic kidney disease, and collectively this is called the cardiorenal metabolic syndrome. Moreover, certain metabolic abnormalities of the heart promote impaired coronary artery endothelial function, diastolic dysfunction and ischemic reconditioning that parallel glomerular hyperfiltration and impairments in proximal tubule handling of sodium and albumin. Another point of focus is the role of the obesity epidemic in promoting the increasing incidence of heart and kidney disease in industrialized countries and the prevailing problems of insufficient exercise and excessive consumption of cheap, unwholesome food in promotion of the cardiorenal metabolic syndrome in both adults and children.CardioRenal Medicine addresses a multidisciplinary audience consisting of nephrologists, cardiologists, nutritionists, endocrinologists, physiologists and general internists.

《心腎醫(yī)學(xué)》雜志探討了肥胖和其他代謝異常促進(jìn)心臟和腎臟疾病(心腎代謝綜合征)發(fā)病和進(jìn)展的機(jī)制。它提供了一個(gè)跨學(xué)科的平臺(tái)，以推進(jìn)研究和臨床實(shí)踐，集中在翻譯問題。人們注意到一些代謝異常與心臟和慢性腎臟疾病聚集在一起，統(tǒng)稱為心腎代謝綜合征。此外，心臟的某些代謝異常會(huì)促進(jìn)冠狀動(dòng)脈內(nèi)皮功能受損、舒張功能障礙和缺血修復(fù)，這些都與腎小球超濾和近端小管鈉和白蛋白處理功能受損同時(shí)發(fā)生。另一個(gè)重點(diǎn)是肥胖流行病在促進(jìn)工業(yè)化國家心臟病和腎臟疾病發(fā)病率不斷增加方面所起的作用，以及在促進(jìn)成人和兒童心腎代謝綜合征方面普遍存在的運(yùn)動(dòng)不足和過度消費(fèi)廉價(jià)、不健康食品的問題。心腎醫(yī)學(xué)面向多學(xué)科觀眾，包括腎病學(xué)家、心臟病學(xué)家、營(yíng)養(yǎng)學(xué)家、內(nèi)分泌學(xué)家、生理學(xué)家和一般內(nèi)科醫(yī)生。