The journal publishes communications dealing with the cell and molecular biology of granulocytes, mononuclear phagocytes, lymphocytes, NK cells, and other cells involved in host defense. Papers covering pathophysiology, cell development, growth and differentiation, extracellular mediators and effector molecules, and receptors, signal transduction, and genes are also included.

該雜志發表了關于粒細胞、單核吞噬細胞、淋巴細胞、NK細胞和其他參與宿主防御的細胞和分子生物學的通訊。包括病理生理學、細胞發育、生長和分化、細胞外介質和效應分子、受體、信號轉導和基因等方面的論文。