Investigative Radiology publishes original, peer-reviewed reports on clinical and laboratory investigations in diagnostic imaging, the diagnostic use of radioactive isotopes, computed tomography, positron emission tomography, magnetic resonance imaging, ultrasound, digital subtraction angiography, and related modalities. Emphasis is on early and timely publication. Primarily research-oriented, the journal also includes a wide variety of features of interest to clinical radiologists.

放射學研究發表關于診斷成像、放射性同位素診斷應用、計算機斷層攝影、正電子發射斷層攝影、磁共振成像、超聲、數字減影血管造影和相關模式的臨床和實驗室調查的原始、同行評議的報告。重點是盡早和及時出版。主要以研究為導向，該雜志還包括臨床放射科醫生感興趣的各種各樣的特點。